Nature News

Modular chemistry click on libraries for practical screens utilizing a diazotization reagent


Kolb, H.C., Finn, M.G. & Sharpless, Ok.B. Click on chemistry: miscellaneous chemical operate from some good reactions. Angew. Chem. Int. Ed. 40, 2004-2021 (2001).


Tornøe, C.W., Christensen, C. and Meldal, M. Peptidotriazoles in stable part: [1,2,3]triazoles by 1,Three-dipolar cyclodispersed 1,Three-dipolar copper-bearing (I) regiospecific terminal alkynes to azides J. Org. Chem. 67, 3057-3064 (2002).


Rostovtsev, V.V., Inexperienced, L.G., Fokin, V.V. and Sharpless, Ok.B. A Huisgen cycloaddition course of in phases: Regioselective copper (I) -ligation catalyzed by azides and terminal alkynes. Angew. Chem. Int. Ed. 41, 2596-2599 (2002).


Dong, J., Krasnova, L., Finn, M. G. and Sharpless, Ok. B. Sulfur Fluoride (VI) Alternate (SuFEx): one other good response for click on chemistry. Angew. Chem. Int. Ed. 53, 9430-9448 (2014).


Kalliokoski, T. Worth-based evaluation of commercially out there constructing blocks for the synthesis of combinatorial libraries. ACS Comb. Sci. 17, 600 to 607 (2015).


Ruff, J. Ok. Derivatives of sulfur oxyfluoride. II. Inorg. Chem. Four, 567-570 (1965).


Shozda, R. J. and Vernon, J. A. Derivatives of azidosulfonic acid. Halides, amides and salts. J. Org. Chem. 32, 2876-280 (1967).


Shozda, R. J. Sulfuryl halides and course of. US Patent 3418088A (1968).


Zeng, X., Gerken, M., Beckers, H. and Willner, H. Anomeric Results in Sulfonyl Compounds: Experimental and Pc Examine of Fluorosulfonyl Azide, FSO2N3, and Trifluoromethylsulfonyl Azide , CF3SO2N3. J. Phys. Chem. A 114, 7624-7630 (2010).


Zeng, X., Beckers, H., Neuhaus, P., Grote, D. and Sander, W. Elusive fluoro-sulfinyl nitrite, FS (O) NO, produced by photolysis of 2N FS (O) remoted on matrix. Z. Anorg. Allg. Chem. 638, 526-533 (2012).


Zeng, X., Beckers, H. and Willner, H. Fluorosulfonylnitrene thermally persistent and surprising formation of the fluorosulfonyl radical. Jam. Chem. Soc. 135, 2096-2099 (2013).


Cavender, C.J. & Shiner, V.J. Trifluoromethanesulfonyl azide. Its response with alkylamines to kind alkylazotures. J. Org. Chem. 37, 3567-3569 (1972).


Alper, P. B., Hung, S.-C. & Wong, C.-H. Diazo switch catalyzed by a steel for the synthesis of amine azides. Tetrahedr. Lett. 37, 6029-6032 (1996).


Nyffeler, P. T., Liang, C.-H., Koeller, Ok.M. and Wong, C.-H. Chemistry of amine-azide interconversion: catalytic switch by diazotransfer and discount of the regioselective azide. Jam. Chem. Soc. 124, 10773-10778 (2002).


Liu, Q. & Tor, Y. Easy conversion of fragrant amines to azides. Org. Lett. 5, 2571-2572 (2003).


Titz, A., Radic, Z., Schwardt, O. and Ernst, B. A protected and handy technique for the preparation of trifluoride, and its use in diazo switch reactions to major amines. Tetrahedr. Lett. 47, 2383-2385 (2006).


Beckmann, H. S. S. & Wittmann, V. Single-vessel process for diazo switch and azide-alkyne cycloaddition: Triazole linkages of amines. Org. Lett. 9, 1-Four (2007).


Lee, C.T., Huang, S. & Lipshutz, B. H. Copper and Coal-catalyzed Tandem Diazo Switch Reactions. Adv. Synth. Catal. 351, 3139-3142 (2009).


Goddard-Borger, E.D. & Stick, R. V. An efficient, cheap and storage secure diazotransfer reagent: imidazole-1-sulfonylazide hydrochloride. Org. Lett. 9, 3797-3800 (2007).


Goddard-Borger, E.D. & Stick, R. V. An efficient, cheap and storage secure diazotransfer reagent: imidazole-1-sulfonylazide hydrochloride. Org. Lett. 13, 2514 (2011).


Guo, T. et al. A brand new portal to click on chemistry SuFEx: a secure fluorosulfuryl imidazolium salt that seems as an "F – SO2 +" donor of unprecedented reactivity, selectivity and area of utility. Angew. Chem. Int. Ed. 57, 2605-2610 (2018).


Schoffelen, S. et al. Introduction of azides in proteins with out metals nor managed pH. Chem. Sci. 2, 701-705 (2011).


Glemser, V. O. & Richert, H. Darstellung and the like by SNF and NSF3. Z. Anorg. Allg. Chem. 307, 313-327 (1961).


Kislukhin, A.A., Hong, V.P., Breitenkamp, ​​Ok.E. and Finn, M.G. Relative alkyne efficiency in copper catalyzed azide-alkyne cycloaddition. Bioconjug. Chem. 24, 684-689 (2013).


Rees, D.C., Congreve, M., Murray, C.W. & Carr, R. Discovery of lead primarily based fragments. Nat. Rev. Drug Discov. Three, 660-672 (2004).


Murray, C.W. & Rees, D.C. The rise of drug discovery primarily based on fragments. Nat. Chem. 1, 187-192 (2009).


Moffat, J. G., Vincent F., Lee, J.A., Eder, J. and Prunotto, M. Alternatives and Challenges of Phenotypic Drug Discovery: An Business Perspective. Nat. Rev. Drug Discov. 16, 531-543 (2017).


Suárez, J.R., B.Trastoy, M. Pérez-Ojeda, M.E., Barrios, R.M. and Chiara, J.L. Nonafluorobutanesulfonyl azide: a storage secure diazo switch reagent for the synthesis of azides from major amines. Adv. Synth. Catal. 352, 2515-2520 (2010).


Katritzky, A.R., Khatib, M.E., Shakov, O.B., Khelashvili, L. and Metal, P.J. Benzotriazol-1-yl-sulfonylazide for diazotransfer and the preparation of azidoacylbenzotriazoles. J. Org. Chem. 75, 6532-6539 (2010).


Fischer, N. et al. Sensitivities of Sure Imidazole-1-Sulfonyl Azide Imide Salts J. Org. Chem. 77, 1760-1764 (2012).


Sure, H. et al. A protected and simple route for imidazole-1-sulfonyl azide imide as a diazotransfer reagent. Org. Lett. 15, 18-21 (2013).


Stevens, M. Y., Sawant, R.T. and Odell, L.R. Synthesis of sulfonyl azides by diazotransfert utilizing an imidazole-1-sulfonyl azide salt: Scope Scanning and 15N NMR experiments. J. Org. Chem. 79, 4826-4831 (2014).


Kitamura, M. et al. Direct synthesis of natural azides of major amines with 2-azido-1,Three-dimethylimidazolinium hexafluorophosphate. EUR. J. Org. Chem. 458-462 (2011).

Leave a Reply

Your email address will not be published. Required fields are marked *