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Wnt and TGFβ coordinate progress and structuring to manage size-dependent habits

1.

Rinkevich, Y. et al. In vivo clonal evaluation reveals the traits of lineage restricted progenitors within the improvement, upkeep and regeneration of mammalian kidneys. Cell Experiences 7, 1270-1283 (2014).

2

Kaufman, J.M., Siegel, N.J. & Hayslett, J.P.Useful and hemodynamic adaptation to progressive kidney ablation. Circ. Res. 36, 286-293 (1975).

three

Fleming, S. et al. Regular ranges of coronary heart fee and respiratory fee in kids from delivery to 18 years: a scientific assessment of observational research. Lancet 377, 1011-1018 (2011).

four

Bryant, P. J. & P., P. Intrinsic and extrinsic management of progress in growing organs. Q. Rev. Biol. 59, 387-415 (1984).

5

Hafen, E. & Stocker, H. How is the scale of cells, organs and physique managed? PLoS Biol. 1, E86 (2003).

6

Oviedo, N.J., Newmark, P.A. and Sánchez Alvarado, A. Allometric scaling and regulation of proportions within the freshwater planar Schmidtea mediterranea. Dev. Dyn. 226, 326-333 (2003).

7.

Stuckemann, T. et al. Self-organized structural antagonist techniques management the upkeep and regeneration of the anteroposterior axis in planarians. Dev. Cell 40, 248 to 263.e4 (2017).

eight

Greatest, J. B., Goodman, A. B. and Pigon, A. Fissioning in Planarians: Management by the Mind. Science 164, 565-566 (1969).

9

Malinowski, P. T. et al. The mechanics dictate the place and the way the freshwater planans make Proc. Natl Acad. Sci. USA 114, 10888-10893 (2017).

ten.

Thomas, M.A., Quinodoz, S. & Schotz, E.-M. Dimension points! J. Stat. Phys. 148, 664-676 (2012).

11

Arnold, C.P. et al. Pathogenic modifications within the endogenous microbiota inhibit regeneration of tissues through the distinct activation of TAK1 / MKK / p38. eLife 5, 5 (2016).

12

Arnold, C., Benham-Pyle, B. and Alvarado, A. S. Planarian fission induction protocol. Nat. Protoc. https://doi.org/10.21203/rs.2.10324/v1 (2019).

13

Gurley, Okay.A., Rink, J.C. & Sanchez Alvarado, A. The β-catenin defines the id of the top in opposition to the tail throughout planar regeneration and homeostasis. Science 319, 323-327 (2008).

14

Roberts-Galbraith, R.H. & Newmark, PA Follistatin antagonizes activin signaling and acts with the notum to direct the regeneration of the planar head. Proc. Natl Acad. Sci. USA 110, 1363-1368 (2013).

15

Hill, E.M. & Petersen, C.P.Wnt / Notum The inhibition of spatial suggestions controls the differentiation of neoblasts to manage the reversible progress of the planar mind. Growth 142, 4217-4229 (2015).

16

Petersen, C. P. & Reddien, P. W. Wnt and the polarity of the primary axis of the physique. Cell 139, 1056-1068 (2009).

17

Reddien, P.W., Bermange, A.L., Kicza, A.M. and Sánchez Alvarado, A. BMP signaling regulates the dorsal planar midline and is critical for uneven regeneration. Growth 134, 4043-4051 (2007).

18

Gaviño, M.A. & Reddien, P.W. A Bmp / Admp regulatory circuit controls the upkeep and regeneration of dorso-ventral polarity amongst planarians. Curr. Biol. 21, 294-299 (2011).

19

Molina, M.D., Saló, E. & Cebrià, F. The BMP pathway is crucial for additional specification and upkeep of the dorso-central axis in regenerating and intact planarians. Dev. Biol. 311, 79-94 (2007).

20

Rink, J.C., Gurley, Okay.A., Elliott, S.A. and Sánchez Alvarado, A. Planarian signaling Hh regulates the polarity of regeneration and relates the evolution of the trail from Hh to cilia. Science 326, 1406-1410 (2009).

21

Sánchez Alvarado, A. and Newmark, P. A. Double-stranded RNA particularly disrupts gene expression throughout planar regeneration. Proc. Natl Acad. Sci. USA 96, 5049-5054 (1999).

22

Cowles, M. W. et al. A genome-wide evaluation of the bHLH gene household in planarians identifies the elements mandatory for neuronal neurogenesis and regeneration in adults. Growth 140, 4691-4702 (2013).

23

Cowles, M.W., Omuro, Okay.C., Stanley, B.N., Quintanilla, C.G. & Zayas, R.M. The lack of operate evaluation reveals a genetic program underlying the upkeep and regeneration of the nervous system in planarians. PLoS Genet. 10, e1004746 (2014).

24

Wenemoser, D., Lapan, S.W., Wilkinson, A.W., Bell, G.W. and Reddien, P.W .. A program of molecular response to wound related to the initiation of regeneration in planarians. Genes Dev. 26, 988-1002 (2012).

25

Arenas, O. M. et al. The activation of planar TRPA1 by reactive oxygen species reveals a conserved mechanism for nociception within the animal. Nat. Neuroscience 20, 1686-1693 (2017).

26

Currie, Okay.W. & Pearson, B.J. lhx1 / 5-1 and pitx transcription elements are mandatory for the upkeep and regeneration of serotonergic neurons in planarians. Growth 140, 3577-3588 (2013).

27

Collins, J. J. III et al. Complete genome analyzes reveal the function of peptide hormones within the improvement of the planar germ line. PLoS Biol. eight, e1000509 (2010).

28

Roberts-Galbraith, R.H., Brubacher, J.L. and Newmark, P. A. A practical genomic display in planarians reveals the regulators of complete mind regeneration. eLife 5, e17002 (2016).

29

Ross, Okay. G. et al. The SoxB1 exercise regulates the regeneration, upkeep and performance of sensory neurons in planarians. Dev. Cell 47, 331-347 (2018).

30

Pearson, B.J. et al. Formaldehyde-based in-situ full-field hybridization methodology for planarians. Dev. Dyn. 238, 443-450 (2009).

31.

King, R. S. & Newmark, P. A. In situ hybridization protocol for improved detection of gene expression within the planar Schmidtea mediterranea. BMC Dev. Biol. 13, eight (2013).

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